A SIMPLE KEY FOR POS88 UNVEILED

to check the effects of many constraints on mutational tolerance in the course of choice, we chose E. coli dihydrofolate reductase (DHFR) as a model process. DHFR is an essential enzyme inside folate metabolism that lessens dihydrofolate to tetrahydrofolate and is essential for thymidine production. making use of this exercise as the basis for Pos8